The Toro Farnese [Museo Archeologico Nazionale di Napoli] is the largest intact statue from antiquity, carved from one piece of marble and restored by Michelangelo [1475-1564], and depicts the death of Circe, tied to the horns of a raging bull by her stepsons Amphion and Zethus for her ill-treatment of their mother Antiope.
An earlier reference to Michelangelo here.